Modern approaches to antibiotic therapy of complicated urinary tract infections given bacterial antibiotic resistance

Abstract

The aim of the study: improving the efficiency of treatment of patients with urinary tract infections given bacterial antibiotic resistance.

Materials and methods. A survey of patients with acute pyelonephritis (n=52) in the aspect of practical application of the modern system of classification of UTI. We determined the sensitivity of the pathogen to different drugs (288 tests for sensitivity test on average of 5.54 per patient).

Results. There was a significant increase in the frequency of multidrug resistant strains of bacteria, especially fluoroquinolones and cephalosporins. The least resistance was observed to carbapenems. Measures are proposed to reduce the emergence of resistant strains, including more active use of carbapenems from the start of therapy in patients with complicated pyelonephritis (with appropriate signs by classification).

Conclusion. The study shows that the resistance of pathogens of acute pyelonephritis is indeed an important issue of urology. Must actively introduce monitoring of resistance of bacterial pathogens in various departments and use it in everyday clinical practice.