The Problem of Pyelonephritis in Terms of Medical and Social Significance
##plugins.themes.bootstrap3.article.sidebar##
##plugins.themes.bootstrap3.article.main##
Abstract
Chronic pyelonephritis (CP) is known for the frequency of visits, hospitalizations, adverse effects. Over time, significant advances in diagnosis and treatment have made the study of medical and social issues relevant.
The objective: the above determined the purpose of the study: to assess the features of epidemiological changes in chronic pyelonephritis among different segments of the adult population in the regions of Ukraine and to identify the dynamics of key performance indicators of specialized care for such patients.
Materials and methods. The official sources of reporting for 2013 - 2020 in Ukraine as a whole in Ukraine and its administrative territories are analyzed, taking into account different segments of the population. The data are statistically processed according to the classical estimation of variation series and comparison of statistical values.
Results. A typical sign is a decrease in registered and newly diagnosed patients with CP. Dominated by people of working age and urban population. Areas where the corresponding indicators are below average, average and above them have been identified. Against the background of a widespread decrease in hospitalizations (by 21.3% in Ukraine) its duration (by 12.7%), mortality doubled to 3.49%. It was confirmed that CP is the second leading cause of chronic kidney disease stage III and IV (21.2% and 20.8% in 2020), with stage V – third (14.04%), in the regions the percentage reached 50–85% at III, 30–48% – IV and 20–33% – V stages. There was a positive decrease (from 27.5% to 20.0%) in cases of primary disability due to pathology.
Conclusions. The peculiarities of the prevalence, incidence of CP in the regions and oblasts of Ukraine among all segments of the population, the nature of changes in the main indicators of inpatient treatment and the dynamics of the effectiveness of specialized care were displayed.
Areas have been identified that require the attention of health authorities, specialists (nephrologists, urologists) in order to develop effective clinical and organizational measures based on an in-depth study of the causes of the situation.
##plugins.themes.bootstrap3.article.details##
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright and grant the journal the first publication of original scientific articles under the Creative Commons Attribution 4.0 International License, which allows others to distribute work with acknowledgment of authorship and first publication in this journal.
References
Anumudu S, Eknoyan G. Pyelonephritis: a Historical Reappraisal. J Am Soc Nephrol. 2019;30(6):914–7. doi: 10.1681/ASN.2019010017.
EAU Guidelines. In: 36th Annual EAU Congress [Internet]. 2021 March 19-23; Milan. Amsterdam: EAU; 2021. Available from: https://www.cancer.eu/eau-21thumb/.
Lisovyy VM, editor. Chronic pyelonephritis: method. decree. for students and interns. Kharkiv: KNMU; 2018. 20 р.
Mykhaylovska NS, editor. Algorithm of activity of the family doctor at the basic diseases of urinary system: teaching method way to practice classes and independent work of VI year students in the discipline. General practice – family medicine. Zaporizhzhya: ZDMU; 2018. 148 р.
Shulyak OV. Infektsiyi sechostatevykh shlyakhiv: piyelonefryt. Ukr med chasopys. 2014;4(102):32–41.
Abolghasemi S, Sali S, Mobasher Aghdam A, Shahrbaf MA. Anti-tuberculosis Induced Stevens – Johnson syndrome Due to Misdiagnosis of Mycobacterium abscessus Urinary Tract Infection as Tuberculosis. Iran J Kidney Dis. 2021;15(3):235–7.
Miftode IL, Nastase EV, Miftode RS, Miftode EG, Iancu LS, Luncă C, et al. Insights into multidrug-resistant K. pneumoniae urinary tract infections: From susceptibility to mortality. Exp Ther Med. 2021;22(4):1086. doi: 10.3892/etm.2021.10520.
Peck J, Shepherd JP. Recurrent Urinary Tract Infections: Diagnosis, Treatment, and Prevention. Obstet Gynecol Clin North Am. 2021;48(3):501–13. doi: 10.1016/j.ogc.2021.05.005.
Batirel A, Regmi SK, Singh P, Mert A, Konety BR, Kumar R. Urological infections in the developing world: an increasing problem in developed countries. World J Urol. 2020;38(11):2681–91. doi: 10.1007/s00345-020-03120-3.
Hudson C, Mortimore G. The diagnosis and management of a patient with acute pyelonephritis. Br J Nurs. 2020;29(3):144–50. doi: 10.12968/bjon.2020.29.3.144.
Chang UI, Kim HW, Noh YS, Wie SH. A comparison of the clinical characteristics of elderly and non-elderly women with community-onset, non-obstructive acute pyelonephritis. Korean J Int Med. 2015;30(3):372–83. doi: 10.3904/kjim.2015.30.3.372.
Herness J, Buttolph A, Hammer NC. Acute Pyelonephritis in Adults: Rapid Evidence Review. Am Fam Physician. 2020;102(3):173–80.
Bordino V, Vicentini C, D’Ambrosio A, Quattrocolo F; Collaborating Group, Zotti CM. Burden of healthcare-associated infections in Italy: incidence, attributable mortality and disability-adjusted life years (DALYs) from a nationwide study, 2016. J Hosp Infect. 2021;113:164–71. doi: 10.1016/j.jhin.2021.04.023.
Chernyak SI, editor. Osnovni pokaznyky invalidnosti ta diyalnosti medykosotsialnykh ekspertnykh komisiy Ukrayiny za 2016 rik: analityko-informatsiynyy dovidnyk. Dnipropetrovsk: Aktsent PP; 2017. 168 р.
Perepelychna RYA, editor. Osnovni pokaznyky invalidnosti ta diyalnosti medyko-sotsialnykh ekspertnykh komisiy Ukrayiny za 2020 rik: analityko-informatsiynyi dovidnyk. Dnipropetrovsk: Aktsent PP; 2021. 188 р.
Kolesnyk MO, editor. Natsionalnyi reiestr khvorykh na khronichnu khvorobu nyrok ta patsiientiv z hostrym poshkodzhenniam nyrok: 2017 rik. Kyiv: DU «Instytut nefrolohii NAMN Ukrainy»; 2018. 183 р.
Kolesnyk MO, editor. Natsionalnyi reiestr khvorykh na khronichnu khvorobu nyrok ta patsiientiv z hostrym poshkodzhenniam nyrok: 2019 rik. Kyiv: DU «Instytut nefrolohii NAMN Ukrainy»; 2020. 179 р.
Arefieva M, Hrytsulya M. Management tactics of patients with asymptomatic bacteria, cystitis and pyelonephritis: Recommendations of the European Association of Urology 2019. Med aspects of Women’s Health. 2020;(1):45–53.
Johnson JR. Acute Pyelonephritis in Adults.N Engl J Med. 2018;378:48–59. doi: 10.1056/NEJMcp1702758.
El-Ghar MA, Farg H, Sharaf DE, El-Diasty T. CT and MRI in Urinary Tract Infections: A Spectrum of Different Imaging Findings. Medicina (Kaunas). 2021;57(1):32. doi: 10.3390/medicina57010032.
Jang YR, Won J, Han J, Chung W, Ahn SJ. Comparison of antimicrobial resistance in patients with obstructive pyelonephritis associated with ureteral stones and uncomplicated pyelonephritis. Medicine (Baltimore). 2022;101(34):e30376. doi: 10.1097/MD.0000000000030376.
Sundquist K, Li X, Jansåker F. Sociodemographic factors and uncomplicated pyelonephritis in women aged 15-50 years: a nationwide Swedish cohort register study (1997-2018). Int J Infect Dis. 2021;111:117–23. doi: 10.1016/j.ijid.2021.08.009.
Sułkowska K, Palczewski P, Furmańczyk-Zawiska A, Perkowska-Ptasińska A, Wójcik D, Szeszkowski W, et al. Diffusion Weighted Magnetic Resonance Imaging in the Assessment of Renal Function and Parenchymal Changes in Chronic Kidney Disease: A Preliminary Study. Ann Transplant. 2020;25:e920232. doi: 10.12659/AOT.920232.
Vernuccio F, Patti D, Cannella R, Salvaggio G, Midiri M. CT imaging of acute and chronic pyelonephritis: a practical guide for emergency radiologists. Emerg Radiol. 2020;27(5):561–7. doi: 10.1007/s10140-020-01788-z.
Saidakova NO, editor. The main indicators of urological care in Ukraine for 2016-2017: departmental publication. Kyiv: Polyum; 2018. 216 р.
Saidakova NO, editor. The main indicators of urological care in Ukraine for 2019-2020: departmental publication. Kyiv: Polyum; 2021: 123 p.
Anumudu S, Eknoyan G. Pyelonephritis: a Historical Reappraisal. J Am Soc Nephrol. 2019;30(6):914–7. doi: 10.1681/ASN.2019010017.
