Syndrome of postejaculation pain and tamsulosin: opportunities and prospects of therapy
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Abstract
The objective: The study is devoted to the evaluation of the clinical efficacy of mono– and combination therapy with tamsulosin in men with chronic prostatitis (CP), both independently and on the background of benign prostatic hyperplasia (BPH) complicated by post-ejaculation pain (PEP).
Materials and methods. The study was conducted in the Department of Sexual Pathology and Andrology of the DU «Institute ofUrology of NAMS of Ukraine» for 1 year. The study included results of outpatient treatment in 145 males (mean age 31±2,5 years) who had a chronic abacaviral prostatitis and/or benign prostatic hyperplasia complicated by painful ejaculation. Patients were divided into three groups: in group I (n=41) patients received standard therapy (nonsteroidal anti-inflammatory drugs, phytopreparations); Group II included patients (n=72) who took standard therapy with tamsulosin inclusion (Flosin®, Menarini Group) at a dose of 0,4 mg/day in the morning, after eating. The third group included patients with verified HAP and BPH (n=32) who received Flosin® 0,4 mg/day in monotherapy for 60 days. The examination was carried out before and after 1, 3 and 12 months after the start of treatment.
Results. The best results were shown in group II patients, where the indicator quickly reached the norm and remained at a high level for 1 year. In individuals of group I, it was less high and did not remain at the desired level throughout the year, while in group III patients, with a low initial evaluation, showed good data throughout the year.
Conclusion. The effectiveness of traditional combined therapy of post-ejaculation pain syndrome was 75,6%, monotherapy of chronic abacterial prostatitis and benign prostatic hyperplasia with tamsulosin – 90,1%, and combination therapy with tamsulosin – 93,1%, which allows us to recommend the use of tamsulosin for the treatment of the above pathology.##plugins.themes.bootstrap3.article.details##
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