Current Concepts of Chronic Pelvic Pain Syndrome


І. І. Горпинченко
К. Р. Нуріманов


Chronic Pelvic Pain Syndrome (CPPS) is a common disease with complex pathogenesis that combines urological, immune, psychological, neurological, endocrine, metabolic, and sexual disorders. The article presents general ideas about CPPS. Features of modern terminology, epidemiology, classification and pathogenesis of the disease, in particular, genetic, endocrine, psychoneurological risk factors for the development of CPPS are presented. The idea of mechanisms of chronic pain development and development, which included the concept of central and peripheral sensitization, description of changes in the content of proinflammatory and anti-inflammatory cytokines, metabolism of tryptophan, glutamate and gamma-aminobutyrate, kinase activity of G-protein 2. The characteristic of clinical forms of CPPS is considered.


How to Cite
Горпинченко, І. І., & Нуріманов, К. Р. (2019). Current Concepts of Chronic Pelvic Pain Syndrome. Health of Man, (4), 7–21.
Distance learning
Author Biographies

І. І. Горпинченко, State Institution «Institute of Urology of NAMS of Ukraine»

Ihor I. Gorpynchenko,

Head of Department of Sexopathology and Andrology

К. Р. Нуріманов, State Institution «Institute of Urology of NAMS of Ukraine»

Kamil R. Nurimanov,

Department of Sexopathology and Andrology


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