Actual Questions of Nonhormonal Stimulation of Spermatogenesis in Male Infertility

##plugins.themes.bootstrap3.article.main##

М. Г. Романюк
О. М. Корнієнко
П. В. Аксьонов

Abstract

Recently, the issue of infertility is very relevant in our country. In this case, the male half of the falls about 50%.

The objective: study of the efficacy and safety of using the drug Zeman in various forms of infertility.

Materials and methods. Regardless of the cause of infertility drugs are being sought that will provide universal stimulating effect on spermatogenesis. One such drug is Zeman (manufactured by Mega Lifesciences Pty. Ltd.,Thailand). Our work has been featured 2 years of experience of use of this multicomponent drug in 1467 patients. The average age of men who participated in the study was 29.4 years. The first (1st) group included 630 patients with secretory infertility, the 2nd group included 510 patients with excretory toxic infertility, and the 3rd group included 327 patients diagnosed with idiopathic infertility.

Results. The result of 3 mths course monotherapy was pregnancy in 214 pairs, regardless of the type of infertility.

Conclusion. The maximum effect was observed in the group of excretory-toxic infertility (ETI), moderate effect was in patients with secretory infertility, and the minimum, but also a clinically significant effect was in idiopathic infertility patients.

##plugins.themes.bootstrap3.article.details##

How to Cite
Романюк, М. Г., Корнієнко, О. М., & Аксьонов, П. В. (2018). Actual Questions of Nonhormonal Stimulation of Spermatogenesis in Male Infertility. Health of Man, (3), 101–106. https://doi.org/10.30841/2307-5090.3.2018.159320
Section
Male infertility
Author Biographies

М. Г. Романюк, State Institution «Institute of Urology of NAMS of Ukraine»

Maksym G. Romaniuk,

Department of Sexopathology and Andrology

О. М. Корнієнко, State Institution «Institute of Urology of NAMS of Ukraine»

Oleksii M. Kornyenko,

Department of Sexopathology and Andrology

П. В. Аксьонов, State Institution «Institute of Urology of NAMS of Ukraine»

Pavlo V. Aksоnov,

Department of Sexopathology and Andrology

References

Nieschlag E, & Behre HM (1997) Andrology – Male reproductive Health and Dysfunction. SpringerVerlag, Berlin, Germany.

Lipshultz LI, Howards SS (1997) Infertility in the Male. Mosby-Year Book, St Louis, USA.

Сексологія та андрологія/ Під ред. акад. О.Ф. Возіанова та проф. І.І. Горпинченко. – К.: Здоров’ я, 1996 р.

Glover TD, Barrat CLR (1999) Male fertility and Infertility. Cambridge University Press, Cambridge, UK. https://doi.org/10.1017/CBO9780511545177

Pasqualotto FF, Locambo CV, Athayde KS, Arap S (2003) Measuring male infertility: epidemiological aspects. Rev. Hosp. Clin. Fac. Med. S. Paulo 58(3):173–178. http://dx.doi.org/10.1590/S0041-87812003000300008

Pasqualotto FF, Pasqualotto EB, Sobreiro BP, Hallak J, Medeiros F, Lucon AM (2006) Clinical diagnosis in men undergoing infertility investigation in a university hospital. Urol Int 76(2): 122–5. https://doi.org/10.1159/000090873