Actual Questions of Nonhormonal Stimulation of Spermatogenesis in Male Infertility

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Published: Oct 31, 2018
DOI: https://doi.org/10.30841/2307-5090.3.2018.159320
Keywords:
Zeman, male infertility, morphofunctional parameters of the ejaculate,

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М. Г. Романюк
State Institution «Institute of Urology of NAMS of Ukraine», Ukraine
О. М. Корнієнко
State Institution «Institute of Urology of NAMS of Ukraine», Ukraine
П. В. Аксьонов
State Institution «Institute of Urology of NAMS of Ukraine», Ukraine

Abstract

Recently, the issue of infertility is very relevant in our country. In this case, the male half of the falls about 50%.

The objective: study of the efficacy and safety of using the drug Zeman in various forms of infertility.

Materials and methods. Regardless of the cause of infertility drugs are being sought that will provide universal stimulating effect on spermatogenesis. One such drug is Zeman (manufactured by Mega Lifesciences Pty. Ltd.,Thailand). Our work has been featured 2 years of experience of use of this multicomponent drug in 1467 patients. The average age of men who participated in the study was 29.4 years. The first (1st) group included 630 patients with secretory infertility, the 2nd group included 510 patients with excretory toxic infertility, and the 3rd group included 327 patients diagnosed with idiopathic infertility.

Results. The result of 3 mths course monotherapy was pregnancy in 214 pairs, regardless of the type of infertility.

Conclusion. The maximum effect was observed in the group of excretory-toxic infertility (ETI), moderate effect was in patients with secretory infertility, and the minimum, but also a clinically significant effect was in idiopathic infertility patients.

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How to Cite
Романюк, М. Г., Корнієнко, О. М., & Аксьонов, П. В. (2018). Actual Questions of Nonhormonal Stimulation of Spermatogenesis in Male Infertility. Health of Man, (3), 101–106. https://doi.org/10.30841/2307-5090.3.2018.159320
Issue
No. 3 (2018)
Section
Male infertility
Copyright (c) 2020 М. Г. Романюк, О. М. Корнієнко, П. В. Аксьонов

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright and grant the journal the first publication of original scientific articles under the Creative Commons Attribution 4.0 International License, which allows others to distribute work with acknowledgment of authorship and first publication in this journal.

Author Biographies

М. Г. Романюк, State Institution «Institute of Urology of NAMS of Ukraine»

Maksym G. Romaniuk,

Department of Sexopathology and Andrology

О. М. Корнієнко, State Institution «Institute of Urology of NAMS of Ukraine»

Oleksii M. Kornyenko,

Department of Sexopathology and Andrology

П. В. Аксьонов, State Institution «Institute of Urology of NAMS of Ukraine»

Pavlo V. Aksоnov,

Department of Sexopathology and Andrology

References

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Glover TD, Barrat CLR (1999) Male fertility and Infertility. Cambridge University Press, Cambridge, UK. https://doi.org/10.1017/CBO9780511545177

Pasqualotto FF, Locambo CV, Athayde KS, Arap S (2003) Measuring male infertility: epidemiological aspects. Rev. Hosp. Clin. Fac. Med. S. Paulo 58(3):173–178. http://dx.doi.org/10.1590/S0041-87812003000300008

Pasqualotto FF, Pasqualotto EB, Sobreiro BP, Hallak J, Medeiros F, Lucon AM (2006) Clinical diagnosis in men undergoing infertility investigation in a university hospital. Urol Int 76(2): 122–5. https://doi.org/10.1159/000090873