A Case of Hyperprogesteronemia in a Young Man

Abstract

The article presents a clinical case of hyperprogesteronemia in a 19-year-old man without visible endocrine and other somatic pathology. Results of laboratory tests: progesterone – 0,441 ng/ml; 0,613 ng/ml (<0,05 –0,149), 17α-hydroxyprogesterone (17α-OHP) – 1,37 ng/ml (0,5 –2,1), DEAS-S – 349; 3 μg/dl (70,2–492,0), androstenedione – 1,21 ng/ml (0,6 –3,1), testosterone (T) total – 21,28 nmol/l (8,64–29,00), T free – 27,93 ng/ml (15–50), estradiol (E2) – 25,28 pg/ml (11,3–43,2), estrone (E1) – 64,9 pg/ml (15,0–65,0), cortisol – 7,37 μg/dl (06:00–10:00; 6,02–18,4), prolactin – 4,91 ng/ml, 2,42 ng/ml (4,04–15,2), lutropin (LH) – 3,2 mIU/ml (1,7–8,6), follitropin (FSH) – 2,6 mIU/ml (1,5–12,4), fasting blood glucose 4,82 mmol/l. This observation is the first in Ukraine described case of hyperprogesteronemia in a healthy young man and is a peculiar phenomenon for further intent study in clinical andrology.