Проблемы идиопатического мужского бесплодия

І. І. Горпинченко, В. С. Савченко, К. Р. Нуріманов, Т. В. Порошина, Г. М. Драннік

Аннотация


В статье представлен анализ эффективности методов лечения мужского идиопатического бесплодия.

Цель исследования: оценить связь показателей спермограммы, цитокинов ТНФ-α и ТФР-β1, антиоксидантных свойств эякулята при мужском идиопатическом бесплодии, а также динамики состояния фертильности под влиянием антиоксидантных средств.

Материалы и методы. В исследование были включены 32 пациента с идиопатическим бесплодием в возрасте 18–45 лет. Изучали динамику показателей спермы (в том числе ее антиоксидантных свойств – НСТ-тест) и цитокинов эякулята (ТНФ-α, ТФР-β1) под влиянием приема препарата Новофертил в течение 6 мес (по 1 капсуле 2 раза в день).

Результаты. Наблюдали статистически значимое (р<0,05) увеличение подвижности сперматозоидов и количество живых сперматозоидов, связь между показателями НСТ-теста и подвижностью сперматозоидов, НСТ-теста и количеством живых сперматозоидов. Иммунологические отклонения в динамике не изменились.

Заключение. Антиоксидантные средства подтвердили эффективность при мужском идиопатическом бесплодии.


Ключевые слова


идиопатическое бесплодие; антиоксиданты; цитокины; лечение

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Литература


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DOI: https://doi.org/10.30841/зм.v0i1 (56).95428

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