DOI: https://doi.org/10.30841/2307-5090.1 (56).2016.95418

The complex usage of tiasid diuretics in metaphylaxis of calcium oxalate nephrolithiasis

В. В. Черненко, Д. В. Черненко, Н. I. Желтовська, В. Й. Савчук

Abstract


The article presents the results of anti recurrent treatment of 150 patients with calcium oxalate nephrolithiasis during 3 years following a new regimen in using the thiazide diuretins which includes thiaxide diuretin – trichlormethiazide, 4 mg/24h, phytopreparation KanefronH, drinking regimen of 1,5-2,5 l, phytotherapy during 3 months. Then 3 months rest and Vit B6 administration 40 mg/24h follow. The recommendatory metaphylaxis is carried out constantly and can be continued for 3-5 and more years. The long term thiazide metaphylaxis against calcium oxalate nephrolithiasis in 38% of patients causes hyperuricosuria of various stage of difficulty, with this 300 mg/24h of allopurinol is recommended between three-months courses of the thiaxide therapy. The proposed metaphylaxis considerably decreases the number of recurrurent calcium oxalate nephrolithiasis: in 39 (26,0%) patients in the group under study against 87 (51,3%) patients in the control group without thiazides. The proposed methods of anti recurrent treatment of patients with calcium oxalate nephrolithiasis is highly effective, safe, of reasonable price.

Keywords


calcium oxalate nephrolithiasis; metaphylaxis; thiazide diuretics

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Copyright (c) 2020 В. В. Черненко, Д. В. Черненко, Н. I. Желтовська, В. Й. Савчук

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ISSN 2412-5547 (Online), ISSN 2307-5090 (Print)