The main indications and practical features of the use of α1-blockers (AB) in urology are analyzes in the article. Studies show that AB usually reduce IPSS by about 30–40% and increase Qmax by about 20–25%. Recently, there have been changes in the AB usage. They are increasingly used for other indications than the treatment of benign prostatic hyperplasia. This is the restoration of urination after urinary retention and in case of urolithiasis to improve the spontaneous passage of stones through the ureters (including women), although these indications are not officially approved. In addition, AB is increasingly being prescribed by physicians of various specialties (such as general practitioners or emergency physicians) rather than just urologists.
The development and implementation of a system of sustained release of tamsulosin has improved its tolerability by reducing the side effects on the cardiovascular system and expanded the possibilities of its use. High-quality generic tamsulosin preparations (such as Tamsin Forte) with a sustained release system can be a worthy alternative to the original drugs.
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