DOI: https://doi.org/10.30841/2307-5090.2.2018.148301

Клиническое значение тестикулярного микролитиаза и определение новых маркеров при герминогенных опухолях яичка

А. В. Сакало

Аннотация


Герминогенные опухоли яичка (ГПЯ) диагностируют чаще в возрасте 20–40 лет, они являются одной из основных причин смерти от онкологических заболеваний в указанной возрастной группе. Рассмотрены новые маркеры, которые потенциально могут быть использованы как мишени для таргетной терапии. Затронута роль микроРНК в качестве молекулярного прогностического маркера при ГПЯ. Отмечено, что обнаружение тестикулярного микролитиаза (особенно двухстороннего) при проведении УЗИ может сопровождаться другими признаками дисгенезии яичек, нарушением фертильности и наличием TIN.

Ключевые слова


герминогенные опухоли яичка; иммуногистохимические маркеры; микролитиаз яичек

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Литература


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