Efficiency of phytotherapy in preventing exacerbations of secondary calculous pyelonephritis and metaphylaxis of urolithiasis


  • Є. А. Литвинець ДВНЗ «Івано-Франківський національний медичний університет»
  • В. Є. Литвинець ДВНЗ «Івано-Франківський національний медичний університет»




urolithiasis, secondary chronic calculous pyelonephritis, treatment, Canephron® N


The objective: to analyse the efficacy and safety of phytopreparation Canephron® N in order to prevent exacerbations of secondary chronic calculous pyelonephritis and metaphylaxis of urolithiasis (MU).

Materials and methods. An open monocentric comparative study in which took part 60 patients with MU and secondary chronic calculous pyelonephritis. The age range of patients was from 28 to 70 years (mean age – 46.3 ± 2.6 years). There were 24 men (40.0%) and 36 women (60.0%). All patients who were included in the  study, on the eve had removal of stones and treatment of pyelonephritis. In order to metaphylaxis of MU and prevention of exacerbation of the secondary chronic calculous pyelonephritis on the basis of a random sample patients were divided into two groups. Patients of the main group (n = 30) received Canephron® N 2 pills or 50 drops 3 times a day for 3 months. Patients of the second group (n = 30) took a phyto tincture «Renal» 50 ml 3 times a  day for 3 months.

Results. Analysis of patients monitoring results shows that the use of Canephron® N for 3 months after the removal of stones and treatment of secondary chronic calculous pyelonephritis significantly reduces the frequency of recurrences of chronic calculous pyelonephritis and formation of recurrent kidney stones.

Conclusion. Canephron® N has no side effects, is well tolerated by patient. And can be recommended for use in preventing formation of recurrent concrements and exacerbations of secondary chronic calculous pyelonephritis.

Author Biographies

Є. А. Литвинець, ДВНЗ «Івано-Франківський національний медичний університет»

E.A. Litvinets

В. Є. Литвинець, ДВНЗ «Івано-Франківський національний медичний університет»

V.E. Litvinets


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