The modern approach to intravesical therapy of chronic cystitis


О. Д. Нікітін


The difficult of treating patients with chronic recurrent cystitis are caused by various factors like virulence of uropathogenic Escherichia coli, and the state of the local resistance of the bladder mucosa and their interaction. Instilan instillations in the treatment of patients with chronic cystitis led to a pronounced positive dynamics of clini cal 95% of patients, as well as to reduce the number of recurrences of cystitis more than 2 times, which greatly improved the quality of life of patients. The results allow us to recommend the use of intravesical sodium hyaluronate for the treatment of various forms of chronic cystitis.


How to Cite
Нікітін, О. Д. (2015). The modern approach to intravesical therapy of chronic cystitis. Health of Man, (4(55), 17–22.
Topical issues
Author Biography

О. Д. Нікітін, Национальный медицинский университет им. А.А. Богомольца

O.D. Nikitin


Moldwin RM, Sant GR. Interstitial cystitis: a pathophysiology and treat ment update. Clin Obstet Gynecol 2002;45: 259.

Oravisto KJ. Epidemiology of intersti tial cystitis. Ann Chir Gynaecol Fenn 1975; 64:75.

Jones CA, Nyberg L. Epidemiology of interstitial cystitis. Urology 1997; 49 (5A Suppl):2.

Parsons CL, Stein PC, Bidair M, Lebow D. Abnormal sensitivity to intrav esical potassium in interstitial cystitis and radiation cystitis. Neurourol Urodyn 1994;13:515.

Parsons CL. Chronic cystitis: epi demiology and clinical presentation. Clin Obstet Gynecol 2002;45:242.

Parsons CL, Lilly JD, Stein P. Epithelial dysfunction in nonbacterial cystitis (interstitial cystitis). J Urol 1991;145: 732.

Daha LK, Riedl CR, Hohlbrugger G, Knoll M, Engelhardt PF, Pfluger H. Comparative assessment of maximal bladder capacity, 0.9) NaCl versus 0.2 M KCl, for the diagnosis of interstitial cystitis: a prospective controlled study. J Urol 2003;170: 807.

Ruggieri MR, Chelsky MJ, Rosen SI, Shickley TJ, Hanno PM. Current find ings and future research avenues in the study of interstitial cystitis. Urol Clin North Am 1994; 21: 163.

Ratliff TL, Klutke CG, McDougall EM. The etiology of interstitial cystitis. Urol Clin North Am 1994; 21:21.

Parsons CL, Housley T, Schmidt JD, Lebow D. Treatmentof interstitial cystitis with intravesical heparin. Br J Urol 1994; 73:504.

Hanno PM. Analysis of long term Elmiron therapy for interstitial cystitis. Urology 1997; 49 (5A Suppl):93.

Morales A, Emerson L, Nickel JC. Intravesical hyaluronic acid in the treat ment of refractory cystitis. Urology 1997;49 (5A Suppl):111.

Wein AJ, Hanno P, Gillenwater JY. An introduction to the problem. In: Hanno P, Staskin DR, Krane RJ, Wein AJ, editors. Cystitis. London: Springer Verlag; 1990. p. 3.

Fall M, Johansson SL, Aldenborg F. Chronic cystitis: a heterogeneous syn drome. J Urol 1987;137:35.

Peeker R, Haghsheno MA, Holmang S, Fall M. Intravesical bacil lus Calmette Guerin and dimethyl sul foxide for treatment of classic and nonulcer interstitial cystitis: a prospective, randomized double blind study. J Urol 2000; 164:1912.