Antioxidant treatment of patients with excretory toxic infertility as a result of chronic abacterial prostatitis

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К. Р. Нуріманов
В. С. Савченко
Т. В. Порошина
О. А. Недогонова
Г. М. Драннік

Abstract

Chronic abacterіal prostatitis difficult and widespread disease, which increase the efficiency of treatment a problem of modern andrology.

The objective: to study the changes of prostatitis symptoms, comorbid mental disorders and subfertility under the influence of combined treatment.

Patients and methods. The 32 patients with chronic abacterial prostatitis aged 18 to 45 years. To assess the symptoms of chronic prostatitis using questionnaire NIH CPSI. Psychological symptoms was studied using that Hospital anxiety depression scale. The concentrations of cytokines in the ejaculate was determined by ELISA. Patients received rectal electrostimulation (10 sessions a day, two courses with an interval of 6 weeks), and functional food supplement Novofertil (2 capsule twice a day for 3 months).

Results. Under the influence of the treatment showed a significant reduction in the symptoms of chronic prostatitis, anxiety and depression, a statistically significant (p<0,05) reduction in the concentration of IL 1β and an increase in the concentration of TGF β1    in the ejaculate. Increasing of the total number of spermatozoa, the   content moving, living and morphologically normal sperm was  observed.

Conclusion. The combination of physical therapy and antioxidant complex Novofertil is effective in the treatment of patients with excretory toxic infertility as a result of chronic abacterial prostatitis.

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Section
Male Infertility and Family Planning
Author Biographies

К. Р. Нуріманов, ГУ «Институт урологии НАМН Украины»

K.R. Nurimanov

В. С. Савченко, ГУ «Институт урологии НАМН Украины»

V.S. Savchenko

Т. В. Порошина, ГУ «Институт урологии НАМН Украины»

T.V. Poroshina

О. А. Недогонова, ГУ «Институт урологии НАМН Украины»

E.A. Nedogonova

Г. М. Драннік, ГУ «Институт урологии НАМН Украины»

G.N. Drannik

References

Горпинченко И.И., Нуриманов К.Р., Порошина Т.В., Савченко В.С., Недогонова О.А., Дранник Г.Н. Комбіноване лікування хворих на хронічний абактеріальний простатит з депресивним синдромом // Здоровье мужчины. – 2016. – No 1. – С. 133–136.

Горпинченко И.И., Нуриманов К.Р., Порошина Т.В., Савченко В.С., Дранник Г.Н. Проблемы идиопатического мужского бесплодия // Здоровье мужчины. – 2016. – No 1. – С. 133–136.